CompletedNot Applicable

Immune Characterization of Subcutaneous Adipose Tissue

United States19 participantsStarted 2014-02

Plain-language summary

The overall goal of this proposal is to characterize the immune cell profile of subcutaneous abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate potential associations between different adipose tissue immune cell types and metabolic profile.

Who can participate

Age range18 Years – 65 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women of all races and ethnicity * Age between 18 and 65 years * Body Mass Index (BMI) ≥ 18.5 kg/m² * Weight stable (+/- 3% during the last 2 months before enrollment) * Women already scheduled for above mentioned procedures Exclusion Criteria: * Diabetes Mellitus * Recent (\<5 years) history of cancer (except in situ ductal breast carcinoma) * Chemotherapy and/or radiation therapy within 4 months before enrollment * Immune system diseases (i.e., autoimmune disorders, acquired immunodeficiency syndrome) * Pregnant or breastfeeding * Take any medication that might affect immune function * Severe organ dysfunction * BMI \<18.5 kg/m² or size of each breast is \>600 grams, if scheduled for bilateral breast reconstruction

What they're measuring

Determine the types of immune cells and the relative prevalence of each type and sub-type, in subcutaneous adipose tissue of normal weight, overweight, obese and lipedema adults.

Timeframe: intraoperative

Trial details

NCT IDNCT02076087

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-09

View on ClinicalTrials.gov More Determine Immune Cell Types in Subcutaneous Adipose Tissue trials