Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease (NCT02075710) | Clinical Trial Compass
UnknownNot Applicable
Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease
United States48 participantsStarted 2013-07
Plain-language summary
The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how much fat is stored in the liver. The study is funded by the National Institutes of Health.
Who can participate
Age range
20 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* overweight or obese men and women
* ages 20-65 years
Exclusion Criteria:
* pregnancy or lactation within the past six months
* type 1 or 2 diabetes mellitus\]
* AST and ALT above upper limit of normal (ULN)
* fasting triglyceride or total cholesterol levels \>ULN
* Hgb below the lower of limit of normal
* positive HIV antibody test or hepatitis serologies
* use of any antidiabetic medications or lipid-lowering drugs
* history of surgery for obesity
* change in body weight \>5% within preceding 6 months (self report)
* claustrophobia, presence of metal implants
* weight over 350 lbs
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Effect of meal composition on fractional de novo lipogenesis (fatty acid synthesis)