CompletedNot Applicable

Imaging Study of Neurovascular Coupling in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

France60 participantsStarted 2014-07-08

Plain-language summary

The aim of this study is to investigate using fMRI methods, EEG and dedicated mathematical models, the potential alterations of neurovascular coupling in CADASIL.

Who can participate

Age range18 Years – 60 Years

SexALL

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Inclusion Criteria: * CADASIL group: typical NOTCH3 mutation, age less than 60 years, rankin score at 0-1, active social insurance Exclusion Criteria: * MRI contra-indications and use of any treatment known to interfere with neurovascular coupling, pregnancy, lack of informed consent

What they're measuring

model-derived parameters of neurovascular coupling

Timeframe: one time point

Trial details

NCT IDNCT02071784

SponsorInstitut National de la Santé Et de la Recherche Médicale, France

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2016-10-24

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