CompletedPhase 4

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

United States22 participantsStarted 2014-01

Plain-language summary

The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup, compared with placebo.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * healthy adult nonsmokers * onset of acute, viral upper respiratory tract infection (common cold) within 72 hours of enrollment Exclusion Criteria: * smokers * history of asthma or other respiratory disorders

What they're measuring

Change in Cough Reflex Sensitivity to Capsaicin

Timeframe: 2 hours after study drug administration

Trial details

NCT IDNCT02062710

SponsorMontefiore Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-06

Results submitted2014-09-16

View on ClinicalTrials.gov More Cough Reflex Sensitivity trials