CompletedPhase 3

Impact of Misoprostol on Blood Loss In Myomectomy Operations

Egypt50 participantsStarted 2013-06

Plain-language summary

The aim of this research work is to assess the effect of using single preoperative dose of rectal misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications

Who can participate

Age range35 Years – 50 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Premenopausal patients aged between 35 to 50 years old. * Five or less symptomatic uterine myomas . * Maximum diameter of the largest myoma is 6 cm . * All myomas are subserous or intramural. * Uterine size less than 24 weeks pregnancy Exclusion Criteria: * History of previous surgery. * Allergy to Misoprostol. * Hypertension. * Cardiac and Pulmonary diseases. * Patients who have bleeding disorders. * Anemia (Hb \< 10g %). * Chronic endocrine or metabolic diseases such as Diabetes. * Obesity (body mass index \> 30 kg/m2). * Cases that will require intraoperative conversion of myomectomy to hysterectomy.

What they're measuring

intraoperative blood loss

Timeframe: time from peritoneum opening till its closure around (1 Hour)

Trial details

NCT IDNCT02061657

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-06

View on ClinicalTrials.gov More Leiomyoma trials