UnknownNot Applicable

Comparative Effectiveness of the Minimally Invasive Coronary Artery Bypass Grafting

Belarus150 participantsStarted 2014-01

Plain-language summary

The purpose of this study is to compare three different revascularization strategies in patients with multi-vessel coronary disease: MICS CABG, OPCABG and ONCABG. The study hypothesis: MICS CABG (Minimally invasive cardiac surgery coronary artery bypass grafting) has advantages in comparison with conventional off-pump (OPCABG) and on-pump coronary artery bypass grafting (ONCABG) concerning major adverse cardiac and cerebral events (MACCE) and procedural success.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Multi-vessel coronary artery disease with ≥ 70% artery stenosis (according to QCA) * II-IV Canadian Cardiovascular Society functional class of angina * Patients at 1 month after acute myocardial infarction * Ability to perform either of revascularization methods (MICS CABG, OPCABG, ONCABG) * Patients must have signed an informed consent Exclusion Criteria: * Pregnancy. * Acute coronary syndrome. * Previous CABG. * Severe comorbidity with high procedural risk for either of the studied strategies. * Mental diseases which block the revascularization procedure. * Severe peripheral artery disease. * Other serious diseases limiting life expectancy (e.g. oncology) * Inability for long-term follow-up. * Participation in other clinical trials. * Single vessel disease. * Need for emergency revascularization (Acute MI, Acute coronary syndrome etc.)

What they're measuring

MACCE

Timeframe: up to 3 years

Trial details

NCT IDNCT02047266

SponsorVitebsk Regional Clinical Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2016-06

Contact for this trial

Aliaksandr A Ziankou, MD, PhD

+375297106526 Zenkov_Al@rambler.ru