Campylobacter Enteritis and Post-Infective Bowel Dysfunction (PI-BD): Role of Antibiotics and Microbiota

Inclusion Criteria: * Age ≥ 18 * Clinical syndrome suggestive of intestinal infection, including symptoms such as new onset of abdominal pain, vomiting, diarrhoea, blood in stools, fever * Submission of stool sample to Nottingham University Hospitals Microbiology Laboratory for investigation of these symptoms * Campylobacter sp. cultured by selective media (standard clinical practice) from this stool sample Exclusion Criteria: * Pregnancy declared by the candidate * History declared by the candidate of pre-existing gastrointestinal disorder, including but not limited to: * Inflammatory Bowel Disease * Coeliac Disease * Pancreatitis * Gallstone disease (biliary colic, cholecystitis) * Diverticulitis * Cancer of the gastrointestinal tract * Irritable Bowel Syndrome * Reported history of previous resection of any part of the gastrointestinal tract other than appendix or gallbladder * Intestinal stoma * Habitual use of opiate analgesics likely to alter bowel function e.g. morphine * Use of antibiotics in the preceding four weeks other than for treatment of index infection. * Use of purgative products/ high dose laxatives for bowel preparation in the four weeks prior to index infection. * Any condition where the candidate is likely to require a course of antibiotics in the next 3 months e.g. severe chronic respiratory disease, recurrent urinary tract infection, lower limb ulceration * Inability to complete the symptom questionnaires e.g. cognitive dysfunction lim…