CompletedPhase 4

Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle

110 participantsStarted 2010-11

Plain-language summary

The study was done to evaluate the effects of the follicular and luteal phases of the menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50 during propofol anesthesia, in patients with and without preoperative intravenous dexmedetomidine .

Who can participate

Age range24 Years – 40 Years

SexFEMALE

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Inclusion Criteria: * a regular menstrual cycle * elective gynecologic surgery Exclusion Criteria: * pregnancy * breastfeeding * obesity * known hypersensitivity to drugs used in the study protocol; * use of psychotropic drugs and steroids within 72 hours before the surgery * central nervous system injury * renal impairment * alcoholism and opioid addiction.

What they're measuring

bispectral index at loss of eyelash reflex

Timeframe: up to 2 years

Trial details

NCT IDNCT02035930

SponsorFudan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-11

View on ClinicalTrials.gov More Abnormal Menstrual Cycle trials