Duration of ANtibiotic Therapy for CEllulitis

Inclusion Criteria: * Admitted to receive intravenous antibiotics for cellulitis/erysipelas * 18 years of age or older * Capable of giving written informed consent, able to comply with study requirements and restrictions Exclusion Criteria: * Allergy for flucloxacillin, other beta-lactam antibiotics or one of the additives, or flucloxacillin induced hepatitis or liver enzyme disorders. * Concurrent use of antibiotics for other indications * Alternative diagnosis accounting for the clinical presentation. * All cases involving any of the following complicating factors: * Use of antibiotics with Gram-positive activity for more than 4 days in the past 7 days * Intensive care unit admission during the last 7 days * Severe peripheral arterial disease (Fontaine IV) * Severe cellulitis necessitating surgical debridement or fascial biopsy * Necrotizing fasciitis * Periorbital or perirectal involvement * Surgery * Life expectancy less than one month * Risk factors associated with Gram-negative pathogens as a causative agent: * Chronic or macerated infra-malleolar ulcers, or infra-malleolar ulcers with previous antibiotic treatment, in patients with diabetes mellitus. * Neutropenia * Cirrhosis (Child-Pugh class B or C) * Intravenous drug use * Human or animal bite * Skin laceration acquired in fresh or salt open water * Fish fin or bone injuries