CompletedNot Applicable

A Randomized Controlled Study of Enteral Nutrition in Septic Shock

United States31 participantsStarted 2014-01

Plain-language summary

There is a paucity of data on the timing and role of enteral nutrition in septic shock. The primary aim of this study is to conduct a phase III single-center pilot randomized controlled trial comparing early trophic enteral nutrition to 'no enteral nutrition' in mechanically ventilated septic shock patients to determine feasibility.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults greater than or equal to 18 years old * Clinical diagnosis of septic shock * Mechanically ventilation anticipated for at least 48 hours Exclusion Criteria: * Do not resuscitate order * Not able to obtain consent * Those not able to be randomized within 18 hours * Those with small bowel ischemia or obstruction * Protracted ileus, intractable vomiting, major gastrointestinal bleeding defined as needing 2 or more units of packed red cells, and any bowel surgery within the previous 30 days prior to intensive care unit admission * Those with a contraindication for placement of a feeding tube

What they're measuring

number of patients consenting to study and remaining compliant with assigned study arm

Timeframe: 46 months

Trial details

NCT IDNCT02025127

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-01

View on ClinicalTrials.gov More Septic Shock trials