Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.

Inclusion Criteria: * Age 18 years or older * Elective patients scheduled to undergo laparoscopic surgery with expected duration \> 2h * Physical status ASA I - III Exclusion Criteria: * Pregnancy * Severe cardiac disease (NYHA class III or IV, acute coronary syndrome, or persistent ventricular tachyarrhythmia) * Previous lung surgery * History of severe chronic obstructive pulmonary disease * Gastro-esophageal pathology (including but not limited to recent gastric or esophageal surgery including bypass/banding, history of esophageal varices, known anatomical gastric or esophageal defects such as strictures, hernias or fistulas) * Mechanical ventilation within the last 30 days * Neuromuscular disease * Consented for another interventional study or refusal to participate in the present study * Hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents