CompletedNot Applicable

Closed-Loop Fluid Administration System Using Hemodynamic Monitors

United States40 participantsStarted 2012-11

Plain-language summary

The purpose of this study is to evaluate the feasibility of a closed-loop (automated) fluid administration system to deliver fluids using feedback from standard operating room hemodynamic monitors. In standard anesthesia care the rate of IV fluid administration to the patient is determined by the anesthesiologist caring for the patient. In this study protocol, the rate of fluid administration will be determined instead by the closed-loop (automated) control system under the supervision of the anesthesiologist. The system will independently decide when to give fluid and at what rate; the supervising anesthesiologist will monitor the system to ensure appropriate volumes are being delivered and to intervene if necessary.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult subjects (over the age of 18) * Subjects undergoing elective major, abdominal surgery * Subjects requiring general anesthesia and mechanical ventilation * Subjects requiring cardiac output monitoring and an arterial line Exclusion Criteria: * Subjects under 18 years of age * Subjects not undergoing surgery * Subjects not requiring general anesthesia or mechanical ventilation * Subjects not requiring cardiac output monitoring or an arterial line * Subjects who are pregnant * Subjects without the capacity to give informed consent

What they're measuring

Fluid Status During Surgery

Timeframe: Duration of Surgery, up to 8 hours

Trial details

NCT IDNCT02020863

SponsorUniversity of California, Irvine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-05

Results submitted2016-03-08

View on ClinicalTrials.gov More Intraoperative Volume Status trials