Active — Not RecruitingEarly Phase 1

A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles

United States20 participantsStarted 2013-11

Plain-language summary

The purpose of this study is to compare the effectiveness of Botox® (Onabotulinum Toxin A) versus Xeomin® (incobotulinum toxin A) for the treatment of forehead and glabellar (vertical lines between the eyebrows) wrinkles.

Who can participate

Age range20 Years – 65 Years

SexALL

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Inclusion criteria

✓. Females and males
✓. In good health
✓. Is 20-65 years of age
✓. Has static and moderate dynamic forehead/glabellar wrinkles
✓. Has willingness and the ability to understand and provide informed consent and communicate with the study staff

Exclusion criteria

✕. Pregnant or lactating
✕. Younger than 20 or older than 65 years of age
✕. Has received the following treatments in the forehead or glabellar region:
✕. botulinum toxin injections in the past 6 months
✕. ablative laser procedure in the past 6 months
✕. radiofrequency device treatment in the past 6 months
✕. ultrasound device treatment in the past 6 months
✕. medium to deep chemical peel in the past 6 months

What they're measuring

Change in glabellar wrinkle score from baseline to 6 months for botox vs. xeomin

Timeframe: At baseline and at 6 months

Change in forehead wrinkle score from baseline to 6 months for botox vs. xeomin

Timeframe: At baseline and at 6 months

Trial details

NCT IDNCT02019004

SponsorNorthwestern University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

View on ClinicalTrials.gov More Wrinkles trials