CompletedNot Applicable

Study Comparing Two Ventilation Modes NAVA (Neurally Adjusted Ventilatory Assist) Mode and Spontaneous Breathing With Inspiratory Pressure Support (IPS) Mode in Consecutive Patients Hospitalized for Acute Respiratory Failure Requiring Mechanical Ventilation With Endotracheal Tube.

France129 participantsStarted 2012-01

Plain-language summary

This is a multicenter, prospective, randomized, open-label study which compared two ventilation modes: spontaneous NAVA mode and spontaneous breathing with IPS mode (the latter is considered as the reference ventilatory mode) in patients admitted to the ICU for acute respiratory failure and ventilated with an endotracheal tube. NAVA mode allows to minimize patient-ventilator disharmony with acceptable tolerance and to preserve spontaneous ventilation.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. norepinephrine \> 0.3 mcg / kg / min;
✓. dopamine \> 10 mcg / kg / min;

Exclusion criteria

✕. Recent gastrointestinal suture ;
✕. Esophageal varices rupture with gastrointestinal bleeding within 4 days prior to inclusion;

What they're measuring

Evaluate the benefit of NAVA mode as compared to IPS mode in terms of duration of spontaneous ventilation 48 hours after inclusion.

Timeframe: Continuous recording during 48 hours following the intubation

Trial details

NCT IDNCT02018666

SponsorClinact

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-08

View on ClinicalTrials.gov More Acute Respiratory Failure trials