Comparing the Location of the Motor Cortex in Children Using Two Methods (NCT02015338) | Clinical Trial Compass
CompletedNot Applicable
Comparing the Location of the Motor Cortex in Children Using Two Methods
United States47 participantsStarted 2014-02
Plain-language summary
Hypothesis: In typically developing children (TDC), use of conventional EEG landmarks to determine the brain area that controls hand function will not differ from TMS-guided determination of individual motor hotspots. In children with hemiparesis, however, those two locations will diverge. The prediction is that TMS will best guide Transcranial Direct Current Stimulation (tDCS) interventions
Who can participate
Age range
8 Years – 17 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Typically Developing Children:
* Ages 8-17
Children with congenital hemiparesis due to hemispheric stroke:
* Ages 8-17
* Equal of greater than 10 degrees of active motion at the metacarpophalangeal joint
* No evidence of seizure activity within the last 2 years.
Exclusion Criteria:
Typically Developing Children:
* neurologic disorders
* indwelling metal
* pregnancy
* history of seizures
Children with hemiparesis:
* Metabolic disorders
* Neoplasm
* Epilepsy
* Disorders of cellular migration and proliferation
* Expressive aphasia
* Pregnancy
* Indwelling metal
* Botulinum toxin or phenol intramuscular block within the one-month preceding TMS application.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
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Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Determine the location of the motor cortex by two different means