The Effect of a Multi-component Weight Management Program on Appetite, Food Preference and Body W… (NCT02012426) | Clinical Trial Compass
CompletedNot Applicable
The Effect of a Multi-component Weight Management Program on Appetite, Food Preference and Body Weight
United Kingdom96 participantsStarted 2014-01
Plain-language summary
The aim of the current study is to demonstrate that a commercial weight management diet (i.e. low energy density) influences satiation, hunger and satiety and leads to lower energy intake during ad-libitum meals and over a full day. We further seek to demonstrate the sustainability of this effect following 12- week weight loss on the weight management program.
* We hypothesise that formulated (low energy) meals will lead to decreased hunger, greater fullness and reduced desire to eat compared to standard meals.
* We hypothesise that the commercial weight management program will lead to greater weight loss compared to control program.
* We hypothesise that formulated meals (high consumer acceptance) will improve hedonic control over eating (lower wanting for high fat food)
* We hypothesise that the commercial weight management program will improve hedonic control over eating (reduced experience food cravings)
Who can participate
Age range
18 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* BMI of 28 - 45 kg/m2
* Reporting an interest in weight loss, not actively participating in a commercial weight loss program,
* Not increased physical activity levels in the past 2-4 weeks
* Able to eat most everyday foods and fruits and vegetables
* Written informed consent to be given
Exclusion Criteria:
* Significant health problems that could cause confounding effects between intervention and control.
* Taking any medication or supplements known to affect appetite or weight within the past month and/or during the study
* Pregnant, planning to become pregnant or breastfeeding
* History of anaphylaxis to food
* Known food allergies or food intolerance
* Smokers and those who have recently ceased smoking
* Participants receiving systemic or local treatment likely to interfere with evaluation of the study parameters
* Those who have previously taken part in a commercial weight loss program in the last 6 months? .
* Participants who work in appetite or feeding related areas
* Participants unable to consume foods used in the study
* Participants who have had bariatric surgery
* Participants with a history of eating disorder
* Presence of untreated hypothyroidism
* Inability to fully comply with intervention or study procedures
* Insufficient English language skills to complete study questionnaires
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.