Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease

Inclusion Criteria: * Patients diagnosed for mild to moderate Aqueous Deficient DED (ADDED), defined as Schirmer 1 \< 10mm; * Patients diagnosed for mild to moderate Evaporative DED (EDED), defined as normal Schirmer 1 and BUT \< 5 seconds; * Patients submitted to refractive surgery, * Patients capable of understanding instructions, signing the term of consent and available to attend all exam visits. Exclusion Criteria: * patients with punctual occlusion, * active ocular infection or inflammatory disease, * history of herpetic keratitis, * contact lens use during trial period, * patients with glaucoma, * any eyelid globe malposition abnormality.