CompletedNot Applicable

Genetic Variants Associated With Adolescent Suicide Attempts

France250 participantsStarted 2013-12

Plain-language summary

Suicidal behaviors is known to aggregate in families. The purpose of this study is to evaluate association between common polymorphisms in genes important for neurobiological pathways linked to suicidal behaviors and suicide attempt among adolescents patient.

Who can participate

Age range

13 Years – 17 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Case : * Age at admission between 13 and 17 years old * Hospitalized for attempted suicide * Absence of prominent mental retardation or organic brain damage * Fluent in French * Able to comprehend the study procedures and to undergo entry assessments safely * Provided written informed consent for study participation, and additional consent from the patient's parents or guardians * Northern and Western European ancestry (HapMap-CEU) * Medical insurance coverage Control : * Healthy adult volunteers * No present or past psychiatric illness * No personal history of suicidal behavior and without a family history of suicide * Provided written informed consent for study participation * Northern or Western European ancestry (HapMap-CEU) * Medical insurance coverage Exclusion Criteria: Case: * Inability to get an informed and valid consent * Home address outside the selected hospitals' geographic areas * Intellectual disability or organic brain damage * Origine ethnique non CEU * Absence of medical insurance coverage * Pregnant or lactating women * Without Northern or Western European ancestry (HapMap-CEU) Control : * Inability to get an informed and valid consent * Intellectual disability or organic brain damage * History of suicidal behavior * Psychiatric disorder, past or present * Family history of suicide * Borderline personality disorder * Absence of medical insurance coverage * Pregnant or lactating women * Without Northern or Western European ances…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Odds ratio (OR) and 95% confidence interval (CI) will be estimated using a logistic regression model to assessing the contribution of each polymorphism as a risk factor in predicting suicidal behavior

Timeframe: Between day 1 and day 5 during hospitalization

Trial details

NCT IDNCT02001649

SponsorUniversity Hospital, Rouen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-07

View on ClinicalTrials.gov More Attempt Suicide trials

Who can participate

Age range

13 Years – 17 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.