The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Process… (NCT02000076) | Clinical Trial Compass
CompletedNot Applicable
The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
Sweden98 participantsStarted 2012-11
Plain-language summary
The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
Who can participate
Age range
20 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 20-30 years of age, inclusive OR 65-75 years of age, inclusive
* Able to understand spoken and written Swedish (in order to understand instructions)
* Normal or corrected-to-normal vision not using glasses
* Not colour blind
* Right-handed
* Free from ferromagnetic objects in body
* No history of any neurologic or psychiatric illness including drug abuse
* No history of diabetes nor hypertension
* No depression according to ratings using the Hospital Anxiety and Depression scale (HAD)
* No insomnia according to ratings using the Insomnia Severity Index (ISI) and Karolinska Sleep Questionnaire (KSQ)
* No use of psychotropic drugs
* Not studying or working in medicine, psychology, nor behavioural science
* Not suffering from severe seasonal allergy
* No use of cortisone, anti-histamines, nor any other immune-modulating drugs
* Habitual intake of no more than 4 cups of coffee per day or the equivalent in terms of caffeine
* No daily use of nicotine
Exclusion Criteria:
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Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Blood oxygen level-dependent response in amygdala to angry faces (t/z-score from statistical parametric mapping)
Timeframe: Change between 1st and 2nd MRI scanning session (approx. 1 month later)