Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy Volunteers

Inclusion Criteria: * Healthy adult male or non-pregnant, non-lactating female, ages 18-49 (inclusive) at time of screening * Have provided written informed consent before screening * Free of clinically significant health problems or clinical lab abnormalities, as determined by pertinent medical history, lab evaluations, and clinical examination before entry into the study * Available and able to participate for all study visits and procedures * If sexually active, known to be at least 1 year post-menopausal, or willing to use an effective method of contraception (e.g., birth control pill, diaphragm, cervical cap, intrauterine device, condom, anatomical sterility \[self or partner\]) from the date of screening until at least 6 months after the last injection * Negative VEEV IgG antibody test result at screening (ELISA) Exclusion Criteria: * History or serologic evidence of prior infection with VEE virus or prior participation in a VEE virus vaccine trial * History of severe local or systemic reactions to any vaccination or a history of severe allergic reactions * History of Guillain-Barre Syndrome * Ongoing participation in another clinical trial * Receipt or planned receipt of any experimental or licensed vaccine, except for a licensed seasonal influenza vaccine, within the period 30 days prior to initial injection through 60 days after the Day 70 follow-up. (\~ 6 month period in total) * Receipt or planned receipt of any allergy treatments involving antigen injections wi…