CompletedNot Applicable

Urinary Markers for Unilateral Kidney Obstruction

Israel53 participantsStarted 2013-10

Plain-language summary

Renal colic is usually caused from an obstructing stone along the ureter. Some of the patients present with a high level of creatinin in the blood, even though there is a normal functioning contralateral kidney. Furthermore creatinin is not an ideal marker for renal function during acute changes. Several works have shown that modern urinary markers such as NGAL (neutrophil gelatinase-associated lipocalin), KIM-1 (Kidney Injury Molecule-1) and others rise earlier and are much more sensitive for kidney insult. There is a lack of research on their role in acute kidney obstruction

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria for stone group: * no known kidney disease * turned to the ER due to renal colic * imaging demonstrates a partially or totally obstructing ureteral stone Inclusion Criteria for non stone group: * turned to the urology department for ambulatory surgery: hydrocelectomy, varicocelectomy, stress incontinence repair,circumcision,cystoscopy Exclusion Criteria: * patients with stones in the contralateral ureter * patients who underwent renal surgery * patients who took NSAID's (nonsteroidal antiinflammatory drugs) in the past week before presentation * patients woth anatomical defects in the kidneys

What they're measuring

urinary markers behavior

Timeframe: one week

Trial details

NCT IDNCT01979042

SponsorCarmel Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-11

View on ClinicalTrials.gov More Renal Colic trials