Use of Probiotics in Oral Health of Patients With Dental Implants

Inclusion Criteria: * Totally edentulous patients subjected to dental implant rehabilitation in one or both arches * Prosthetic restoration in function for at least 24 months * Healthy individuals without known disease Exclusion Criteria: * Patients receiving any kind of local or systemic decontamination treatment of the oral cavity (e.g., antibiotics or rinses) in the last 3 months, or periodontal treatment in the last 6 months * Uncontrolled periodontal disease * Patients with immune deficiencies, diabetes, rheumatoid disease, head and neck radiotherapy, bisphosphonate treatment, chemotherapy or anticoagulation * Patients with dental implants presenting intraoral exposure of the rough portion of any implant * Smokers * Incomplete protocols due to a lack of patient cooperation: a) failure to follow the treatment instructions; b) failure to report to the visit after one month of follow-up * Failure to provide informed consent to participation the study * Patients presenting at least one implant with peri-implantitis