CompletedNot Applicable

Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Ulcer in Bladder Pain Syndrome Patients

South Korea126 participantsStarted 2012-06

Plain-language summary

On the EAU (European Association of Urology) guidelines, the ulcer type bladder pain syndrome (BPS) should be treated with transurethral resection (TUR) or coagulation (TUC) of ulcer. But, Up to date, there was no study to compare the therapeutic efficacy of TUR with TUC in ulcer type BPS patients. We assume TUR have a more therapeutic effect than TUC.

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion criteria

✓. Male and female aged 18 yrs or greater
✓. Patients diagnosed with BPS(Bladder Pain Syndrome)
✓. Symptom persisted more than 6 months
✓. Pain VAS ≥4
✓. O'Leary-Sant Interstitial Cystitis questionnaire (IC-Q) scores 12 or greater with pain and nocturia domain scores \> 2.
✓. Pelvic Pain and Urgency/Frequency Patient Symptom Scale(PUF) \>13
✓. No history of cystoscopy within 2yrs.

Exclusion criteria

✕. History of augmentation cystoplasty or previous transurethral coagulation/resection due to BPS
✕. Child-bearing potential, pregnant or nursing women.
✕. Mean voided volume lesser than 40ml or over than 400ml.
✕. Hematuria exceeds 1+ in the urinary dipstick (dipstick) examination.
✕. Urinary tract infection during run-in periods.
✕. Genitourinary tuberculosis or bladder,urethral and prostate cancer
✕. Recurrent urinary tract infection

What they're measuring

Recurrence-free survival between TUC and TUR

Timeframe: Until 12 months after the last subject be enrolled

Trial details

NCT IDNCT01963988

SponsorSamsung Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-10

View on ClinicalTrials.gov More Bladder Pain Syndrome trials