UnknownNot Applicable

Primary PCI in Patients With ST-elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization

Denmark650 participantsStarted 2011-05

Plain-language summary

In patients with ST-elevation myocardial infarction (STEMI) the primary treatment is acute angioplasty of the acute occlusion (culprit lesion). In STEMI patients with multi vessel disease (MVD) no evidence based treatment of the non-culprit lesions exists. We aim to provide evidence as to whether full revascularization or revascularization of the culprit lesion only provides the best prognosis for the patient.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years. * Acute onset of chest pain of \< 12 hours' duration. * ST-segment elevation ≥ 0.1 millivolt in ≥ 2 contiguous leads, signs of a true posterior infarction or documented newly developed left bundle branch block. * Culprit lesion in a major native vessel. * MVD (non-culprit vessels with angiographic stenosis \>50%) * Successful primary PCI Exclusion Criteria: * Pregnancy. * Known intolerance of acetylsalicylic acid, clopidogrel, heparin or contrast. * Inability to understand information or to provide informed consent. * Haemorrhagic diathesis or known coagulopathy. * Stent thrombosis * Significant left main stem stenosis * Cardiogenic shock at admittance

What they're measuring

All cause death, myocardial infarction or revascularization

Timeframe: 1 year

Trial details

NCT IDNCT01960933

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-02

View on ClinicalTrials.gov More ST-elevation Myocardial Infarction trials