Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-rel… (NCT01954368) | Clinical Trial Compass
CompletedPhase 4
Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay
France144 participantsStarted 2014-01
Plain-language summary
Non-invasive and simple, intranasal (IN) route of administration seems promising for pain management in the Emergency Department (ED), especially when used precociously by triage nurse to rapidly deliver the first opioid dose to severely painful patients.
This randomized double-blind placebo-controlled study will focus on severe traumatic pain experienced by adults admitted in our ED.
We hypothesized that, in addition to traditional morphine titration, a single dose of IN sufentanil given at triage would significantly increase the proportion of patients relieved 30 minutes after their ED admission.
Time to discharge, proportion of side effects and satisfaction rates will also be recorded.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Single traumatic limb injury.
* Severe pain (score \> 5/10 on numerical pain scale)
* Age ≥ 18 years and \< 75 years
Exclusion Criteria:
* Abdominal, thoracic, vertebral or cranial injury associated
* Hemodynamic instability (systolic blood pressure \< 100 mmHg and/or blood pulse \> 110 / min)
* Oxygen saturation \< 96% on room air
* Chronic respiratory, renal or cardiac failure
* Impaired mental status (Glasgow Coma Scale \< 15)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.