CompletedPhase 4

Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay

France144 participantsStarted 2014-01

Plain-language summary

Non-invasive and simple, intranasal (IN) route of administration seems promising for pain management in the Emergency Department (ED), especially when used precociously by triage nurse to rapidly deliver the first opioid dose to severely painful patients. This randomized double-blind placebo-controlled study will focus on severe traumatic pain experienced by adults admitted in our ED. We hypothesized that, in addition to traditional morphine titration, a single dose of IN sufentanil given at triage would significantly increase the proportion of patients relieved 30 minutes after their ED admission. Time to discharge, proportion of side effects and satisfaction rates will also be recorded.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Single traumatic limb injury. * Severe pain (score \> 5/10 on numerical pain scale) * Age ≥ 18 years and \< 75 years Exclusion Criteria: * Abdominal, thoracic, vertebral or cranial injury associated * Hemodynamic instability (systolic blood pressure \< 100 mmHg and/or blood pulse \> 110 / min) * Oxygen saturation \< 96% on room air * Chronic respiratory, renal or cardiac failure * Impaired mental status (Glasgow Coma Scale \< 15)

What they're measuring

Pain relief assessment

Timeframe: 30 minutes after ED admission

Trial details

NCT IDNCT01954368

SponsorCentre Hospitalier Universitaire de Nice

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-03

View on ClinicalTrials.gov More Single Traumatic Limb Injury With Severe Pain (Score > 5/10 on Numerical Pain Scale) trials