CompletedNot Applicable

MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries

Norway70 participantsStarted 2012-05

Plain-language summary

This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period. The purpose is to evaluate the coronary arteries and direct and indirect findings of coronary artery disease/complications with 3 tesla magnetic resonance imaging.

Who can participate

Age range10 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinical diagnosis of transposition of the great arteries with or without ventricular septum defect * Surgically corrected during neonatal period with arterial switch procedure Partial or total Exclusion Criteria: * Heart arrhythmias * Known allergic reaction to gadolinium based contrast media * Reduced renal function (below 60 ml/min/1,73m2)

What they're measuring

Direct visualization and status of the coronary arteries, global volume measurements, global and regional strain (myocardial contractility), extravascular, extracellular tissue volume fraction and late enhancement (myocardial fibrosis).

Timeframe: 10-15 years after surgery

Trial details

NCT IDNCT01916499

SponsorOslo University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-04

View on ClinicalTrials.gov More Transposition of Great Vessels trials