CompletedNot Applicable

Use of Dehydroepiandrosterone (DHEA) in Women With Normal and Poor Ovarian Reserve Undergoing IVF

Hong Kong104 participantsStarted 2010-10

Plain-language summary

The aim of the study is to evaluate the effect of DHEA supplement on ovarian reserve markers, ovarian response to gonadotrophins and cycle outcomes in patients with normal and poor ovarian reserve. Study Hypotheses: 1. DHEA supplementation would improve markers of ovarian reserve and ovarian response to low dose FSH stimulation in both normal and poor responders 2. DHEA supplementation would improve IVF cycle outcomes

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Indicated for IVF treatment according to our standard department protocol * Age \< 40 * Regular menstrual cycles (21-35 days with \</= 4 days inter-cycle variation) * AFC not more than 15 Exclusion Criteria: * Previous chemotherapy or pelvic irradiation * Polycystic ovarian syndrome or polycystic ovaries * On hormonal supplementation for any indication at the time of recruitment (e.g. estrogen, testosterone or DHEA)

What they're measuring

Antral follicle count

Timeframe: after 12 weeks of DHEA

Trial details

NCT IDNCT01915186

SponsorThe University of Hong Kong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-01

View on ClinicalTrials.gov More Female Infertility Due to Diminished Ovarian Reserve trials