Active — Not RecruitingNot Applicable

An Optimized Programming of Healthy Children (APPROACH)

Denmark280 participantsStarted 2014-01-04

Plain-language summary

The Nutrition Research Unit at Copenhagen University Hospital Herlev will during the fall 2013 initiate a randomized and controlled intervention study engaging 390 obese pregnant women. The overall aim of APPROACH is to investigate how an optimal diet during pregnancy influences the programming of the offspring. The children will after birth be included in a prospective cohort according to maternal randomization and examined six times from delivery until the age of nine years.

Who can participate

Age range18 Years – 42 Years

SexFEMALE

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Inclusion Criteria: * Birth planed at Copenhagen University Hospital Herlev * Pre-pregnancy BMI 28-45 * Age 18-42 years * Speak and understand oral and written Danish * Singleton pregnancy Exclusion Criteria: * Multiple pregnancy * History of spontaneous abortions or gestational diabetes or preeclampsia or spontaneous preterm birth * Dairy product intolerant or allergic * \> 10 kg weight change during the past year * Abuse of alcohol or drugs (\>14 units of alcohol per week) * Critical or chronic disease: diabetes, kidney disease, medically treated heart diseases or arthritis, sarcoidosis, tuberculosis, cancer, liver disease, inflammatory gastrointestinal or lung disease, known active metabolic disease.

What they're measuring

Gestational weight gain

Timeframe: Gestational week 14, 15, 17, 21, 25, 28, 36, 39

Trial details

NCT IDNCT01894139

SponsorUniversity of Copenhagen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-01

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