CompletedPhase 4

High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication

Thailand118 participantsStarted 2013-05

Plain-language summary

The purpose of this study is to compare the efficacy between 1-day high dose PPI-based triple therapy vs. 10-day sequential therapy for Helicobacter pylori eradication in functional dyspepsia patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Functional dyspepsia patients (Rome III) with rapid urease test positive * Age ≥ 18 years old * No history of HP eradication Exclusion Criteria: * Recent use of PPI, H2RA, NSAID, Antibiotics within 2 weeks * Currently use of anticoagulants or ketoconazole * C/I for gastric biopsy * History of gastric surgery * Comorbidity: ESRD, advanced cirrhosis, AIDS, stroke (bed ridden) * Pregnancy or lactation * Allergy to studied drugs

What they're measuring

Eradication rate

Timeframe: 4 weeks after the end of intervention

Trial details

NCT IDNCT01888237

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-08

View on ClinicalTrials.gov More Dyspepsia trials