CompletedPhase 3

Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus

France434 participantsStarted 2013-06-26

Plain-language summary

The main purpose of this study is to know on one hand if lorazepam is more (effective) than clonazepam and on the other hand if lorazepam is also effective as the association clonazepam + fosphenytoin in out-of-hospital treatment of the generalized convulsive status epilepticus in adult patients.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. convulsive seizures at the time of treatment and were reported by reliable witnesses to have been continuously convulsing for longer than 5 minutes, without regaining consciousness, or
✓. if they were having more than 2 repeated convulsive seizures at the time of treatment without regaining consciousness

What they're measuring

Percentage of patient with a cessation of seizures and absence of recurrence

Timeframe: between 20 and 60 minutes after the beginning of the treatment

Trial details

NCT IDNCT01870024

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-02-23

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