UnknownPhase 2

Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence

Iran144 participantsStarted 2012-10

Plain-language summary

* Purpose of study : to determine the preventive effect of acetazolamide administration, prone positioning, and the combination of both following the neurosurgical interventions in lumbosacral region for cerebrospinal fluid (CSF) leak, CSF collection and wound dehiscence. * Sample size: 144 * intervention groups: * Group A: Acetazolamide administration for 10 days * Group B: prone positioning for 10 days * Group C: Acetazolamide administration and prone positioning for 10 days * Group D: no intervention * Period of study: Autumn 2012 to the end of winter of 2015

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Untethering surgery for primary tethered cord caused by thick filum * Lipomyelomeningocele * Split cord malformation management * Untethering surgery in uncomplicated Dermal sinus * Tumors needing intradural management in lumbosacral region * Having any other disease with similar management technique Exclusion Criteria: * Infected dermoid tumors * Intramedullary abscess * Myelomeningocele surgery and related reoperation * Meningocele * Presence of hydrocephalus

What they're measuring

Cerebrospinal fluid leakage

Timeframe: 1month

Cerebrospinal fluid collection

Timeframe: 1 month

wound dehiscence

Timeframe: 1 month

Trial details

NCT IDNCT01867268

SponsorTehran University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-04

Contact for this trial

Farideh Nejat, MD

+98 912 1494064 nejat@tums.ac.ir

View on ClinicalTrials.gov More Fibrolipoma of Filum Terminale trials