Efficacy of Surgical Preparation Solutions in Knee Surgery

Inclusion Criteria: * \>18 years old and less than 89 * Undergoing primary total knee arthroplasty * Not undergoing surgical intervention for infection Exclusion Criteria: Injury due to trauma * Open wound at the incision site determined by pre-op history and physical * Abrasion in the vicinity of the planned incision site determined by pre-op history and physical * Active infection at or near the surgical incision site determined by pre-op history and physical * Active infection somewhere else in the body determined by pre-op labs and history and physical * Prior history of surgical infection or bacteremia determined by pre-op history and physical * History of rheumatoid arthritis determined by pre-op history and physical * History of autoimmune disorder determined by pre-op history and physical * Immunosuppressed patient determined by pre-op history and physical * Known allergy to iodine, isopropyl alcohol or Chlorhexidine