Neuropsychological and Brain Medical Imaging Study in Patients With Brain Damage

Inclusion Criteria: * age between 18 and 80 years * french language * effective contraception for women during the study * informed consent * no alcohol intake the day before the exam * for patients only, focal cerebral lesion (stroke, malformation, tumor, inflammatory, infectious, traumatic), neonatal pathology or degenerative disease with cognitive deficit Exclusion Criteria: * for healthy volunteers: previous neurological history (except non complicated migraine), previous psychiatric history (except depression with good evolution or anxiety with maximum one anxiolytic treatment), or severe cranial traumatism * for patients: vigilance disorders, severe depression or anxiety. * for both: psychotropic medication other than a hypnotic or an anxiolytic at low doses without dose modification for at least one month, severe visual or auditory impairment, patient without judicial or administrative liberty, measure of legal protection or no capable to express their consent, pregnancy or breastfeeding, contraindication for MRI, participation in another trial or former involvement in another trial within one month