Enhancing Neuroplasticity and Frontal Lobe Function in Patients With Mild Alzheimer's Disease

Inclusion Criteria for patients: * Age 65 or above * Meet NINCDS-ADRDA and DSM-IV TR criteria for a current diagnosis of Alzheimer's Disease * Stable does of acetylcholinesterase inhibitors for at least 3 months * Willingness and ability to speak English * Willingness and ability to provide informed consent * Corrected visual ability that enables reading of newspaper headlines and corrected hearing capacity that is adequate to respond to a raised conversational voice. Exclusion Criteria for patients: * Meets criteria for an Axis I diagnosis within the past 12 months other than Dementia of the Alzheimer type. * Mini Mental Status Examination score of 16 or less as described above * Meets diagnostic criteria for current alcohol or other drug dependence within 6 months of testing * Electroconvulsive Therapy (ECT) within 6 months of testing. * Left handedness. * Incompetency to consent * Any contraindication for TMS Inclusion Criteria for healthy controls: * Age 65 or above * Willingness and ability to speak English * Willingness and ability to provide informed consent * Corrected visual ability that enables reading of newspaper headlines and corrected hearing capacity that is adequate to respond to a raised conversational voice. Exclusion Criteria for healthy controls: * Meets criteria for an Axis I diagnosis other than simple phobias or adjustment disorder. * Other neurological disorder affecting central nervous system. * Psychotropic medication except for sedative /hypn…