CompletedNot Applicable

Influence of High Intensity Exercise on Insulin Resistance, Muscle Contractile Properties, Aerobic Capacity and Body Composition in Multiple Sclerosis

Belgium34 participantsStarted 2013-03

Plain-language summary

The purpose of this study is to investigate the effects of a combined training programme and a high intensity interval training programme on insulin resistance, muscle strength/ muscle contractile properties, aerobic capacity and body composition in MS patients. It is assumed that the the above mentioned clinical parameters will improve due to physical exercise.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed MS according to the McDonald criteria * Expanded Disability Status Scale (EDSS) between 0.5 and 6 * Be able to train 5 times in 2 weeks at the University Exclusion Criteria: * Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases (like diabetes type 2) * Having had an relapse in a period of 3 months prior to the start of the intervention period * Having an relapse during the intervention period * Pregnancy and other contra indications for physical activity * Mental disorders

What they're measuring

insulin sensitivity (insulin profile)

Timeframe: change from baseline to 12 weeks

muscle contractile properties

Timeframe: from baseline to 12 weeks

Trial details

NCT IDNCT01845896

SponsorBert Op't Eijnde

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-03

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