Non-invasive Measuring of Cerebral Perfusion After Severe Brain Injury With Near-infrared-spectroscopy and ICG

Inclusion Criteria: * Patients over 18 years * onset of clinical symptoms of subarachnoid or intracranial haemorrhage or trauma suffered less than 72h * indication for implanting a tissue oxygen and intracranial pressure probe * A signed informed consent by the patient or legal guardian Exclusion Criteria: * Persistent epidural, subdural or subcutaneous hematoma in planned area of the NIRS optode * Open injuries in the area of the planned optodes * Malignant primary disease under chemotherapy * pregnancy * bleeding disorder * In the short term unfavorable prognosis (eg, bilateral wide and light-fixed pupils) * Patients with pacemakers or where no MRI compatibility is due to non- removable metal parts * contraindications for contrast media in CT (eg, iodine allergy) * Untreated hyperthyroidism * End Stage Renal Disease * severe psychomotor agitation