Evaluation of the Metabolome in Diverticular Disease

Inclusion Criteria: * Female patients over 18 years of age * Patient with a diagnosis of uncomplicated symptomatic diverticular disease diagnosed for the first time * Patient able to comply with the procedures of the Protocol * Ability to sign written informed consent Exclusion Criteria: * Segmental colitis associated with diverticulosis * Inflammatory Bowel Disease * Active or recent peptic ulceration * Chronic renal failure * Known allergy to products in the study * Use of lactulose-lactitol in the two weeks prior to enrollment and during the study * Previous surgery of the colon * Diverticular disease-related complications (fistulas, abscesses, stenosis) * Use of probiotics in the 4 weeks prior to enrolment * Renal, hepatic, hematologic, cardiovascular, pulmonary, neurological, psychiatric, immunological, gastrointestinal or endocrine disease, if found to be clinically significant * Active malignancy or history of any type of malignancy. * Recent history or suspicion of abuse of alcohol or drugs * Women who are pregnant, nursing or of childbearing age not using appropriate contraceptive methods * Any severe pathology that may interfere with the treatment * Inability to provide written informed consent * Not sufficiently reliable or presence of conditions that can result in non-compliance / patient adherence to the Protocol * Previous participation in another study * Lack of compliance towards the products in the study