Ketamine Versus Etomidate for Rapid Sequence Intubation

Inclusion Criteria: * 18 years of age * Undergoing rapid sequence intubation (RSI) in the Emergency Department Exclusion Criteria: * Known contraindication to ketamine or etomidate * Patient has a condition in which an increase in heart rate or blood pressure would be hazardous, as judged by the treating physician * Patient is known or suspected of having increased intracranial pressure, based on the history and physical examination performed by the treating physician. * Females of child-bearing age, defined as 18-50 years, who do not have a documented pregnancy test in this institution confirming that they are not pregnant or who do not have a confirmed surgical procedure preventing pregnancy, i.e., tubal ligation, hysterectomy. The timing of the pregnancy test at which the investigative team will consider a subject to be non-pregnant is a documented negative test during current hospitalization or upon direct transfer from outside institution during current illness. * Patient declines participation in the trial by wearing a bracelet marked "KvE declined" * Prisoner