CompletedNot Applicable

Pulse Pressure Variation for Prediction of Fluid Responsiveness in Coronary Artery Disease Patients With Diastolic Dysfunction

South Korea66 participantsStarted 2012-01

Plain-language summary

The investigators hypothesized that predictability of pulse pressure variation (PPV) on fluid responsiveness would be reduced in patients with coronary disease who have diastolic dysfunction.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients older than 20 years * scheduled for elective coronary artery bypass grafting * normal diastolic function (E/E' \< 8) or diastolic dysfunction (E/E' \>15) according to preoperative Echocardiographic evaluation Exclusion Criteria: * arrythmia, * reduced left ventricular function (ejection fraction \< 40%) * valvular heart disease requiring concomitant surgical correction * pulmonary hypertension (mean pulmonary arterial pressure ≥30 mm Hg) * peripheral arterial occlusive disease, pulmonary disease (asthma, chronic obstructive pulmonary disease, and lung resection) * end-stage renal disease

What they're measuring

predictability of pulse pressure variation (PPV) on fluid responsiveness in patients with coronary disease who have normal diastolic function and diastolic dysfunction.

Timeframe: 10 minutes after fluid replacement

Trial details

NCT IDNCT01819571

SponsorYonsei University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-10

View on ClinicalTrials.gov More Fluid Responsiveness Predictability trials