CompletedEarly Phase 1

Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery

France30 participantsStarted 2006-03

Plain-language summary

The idea is to assess the predictive value of flow magnetic resonance imaging (flow MRI) for patient suffering normal pressure hydrocephalus (NPH) planned for surgery. By now, the depletive lumbar puncture is the best test assessing the efficacy of a forthcoming surgery. The idea is to demonstrate that flow MRI can be as effective as lumbar puncture in term of predictive value of surgery response. In that way, cerebrospinal fluid (CSF) dynamics are evaluated by a single non invasive examination. CSF flow is measured at the Sylvius' aqueduct, cervical, arachnoid space and 4th ventricle levels.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age: over 20 years * diagnostic of normal pressure hydrocephalus * ventricular dilation visible on radiological examination * patients gave their written informed consent Exclusion Criteria: * age: less than 20 years * MRI contra-indication * pregnancy * lumbar puncture within 48 hours before MRI * cardiac arrhythmia * cerebral/lacunar stroke

What they're measuring

CSF stroke volume

Timeframe: Day 1

Trial details

NCT IDNCT01815775

SponsorCentre Hospitalier Universitaire, Amiens

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-07

View on ClinicalTrials.gov More Normal Pressure Hydrocephalus trials