UnknownNot Applicable

Revitalization of Immature Permanent Teeth With Necrotic Pulps Using SHED Cells

China80 participantsStarted 2013-02

Plain-language summary

Revitalization of Young Immature Permanent Teeth With Necrotic Pulps Using Autologous Stem Cells from Human Exfoliated Deciduous Teeth

Age range7 Years – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Those who has signed the informed consent.
✓. Those who are between 7-years-old to 12-years-old.
✓. Those with at least one young permanent teeth with pulp necrosis which caused by trauma or permanent incisor avulsed by trauma.
✓. Those who can provide the health deciduous teeth.
✓. Those who have accomplished initial preparation and have been showing good compliance.
✓. Those whose guardians understand the purposes of the trial and are capable of making an independent decision to comply with trial requirements
✓. Those who are able to visit our hospital in accordance with the trial schedule

✕. Those in an extremely poor nutritional condition (serum albumin concentration \<2 g/dL)
✕. Those whose guardians would not cooperate with the treatment.
✕. Those who has uncontrollable oral disease.
✕. Those with severe dental fear.
✕. Those with coexisting mental or consciousness disorder.
✕. Those with teeth dysplasia and/or hereditary disease history.
✕. Those with systemic disease which may affect the postoperative healing.
✕. Those with bruxism and malocclusion.

Pulp and Apical regeneration

Timeframe: 1 year following transplantation

NCT IDNCT01814436

SponsorAir Force Military Medical University, China

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-07

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