Revitalization of Immature Permanent Teeth With Necrotic Pulps Using SHED Cells (NCT01814436) | Clinical Trial Compass
UnknownNot Applicable
Revitalization of Immature Permanent Teeth With Necrotic Pulps Using SHED Cells
China80 participantsStarted 2013-02
Plain-language summary
Revitalization of Young Immature Permanent Teeth With Necrotic Pulps Using Autologous Stem Cells from Human Exfoliated Deciduous Teeth
Who can participate
Age range
7 Years – 12 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Those who has signed the informed consent.
. Those who are between 7-years-old to 12-years-old.
. Those with at least one young permanent teeth with pulp necrosis which caused by trauma or permanent incisor avulsed by trauma.
. Those who can provide the health deciduous teeth.
. Those who have accomplished initial preparation and have been showing good compliance.
. Those whose guardians understand the purposes of the trial and are capable of making an independent decision to comply with trial requirements
. Those who are able to visit our hospital in accordance with the trial schedule
Exclusion criteria
. Those in an extremely poor nutritional condition (serum albumin concentration \<2 g/dL)
. Those whose guardians would not cooperate with the treatment.
. Those who has uncontrollable oral disease.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pulp and Apical regeneration
Timeframe: 1 year following transplantation
Trial details
NCT IDNCT01814436
SponsorAir Force Military Medical University, China