CompletedNot Applicable

Ischemic Postconditioning in Cardiac Surgery

Norway209 participantsStarted 2013-01

Plain-language summary

Ischemic postconditioning by repetitive cycles of reperfusion and ischemia has been proven both in animal models and in humans. This study aims to investigate the effect of ischemic postconditioning on postoperative hemodynamic function in a standard heart surgery patient population.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Patients undergoing elective surgery of the ascending aorta or the aortic valve \- Exclusion Criteria: * Coronary artery disease requiring bypass surgery * Tricuspid valve surgery * Mitral valve surgery * Atrial fibrillation (permanent or paroxysmal with or without concomitant ablation procedure) * Patients on per oral or parenteral steroid therapy (inhalational steroids are allowed) * Patients with autoimmune diseases * "Redo" operations * Active endocarditis (ongoing antibiotic therapy) * On the discretion of the operating surgeon or anaesthesiologist

What they're measuring

Change in cardiac index between the groups during the first postoperative day

Timeframe: The first postoperative day: measurements at 2, 8 and 18 hrs postoperatively

Trial details

NCT IDNCT01813968

SponsorOslo University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-06

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