The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Tr… (NCT01813565) | Clinical Trial Compass
TerminatedNot Applicable
The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome.
Stopped: No benefit of intravesical instillation of Hyaluronic Acid/Chondroitin Sulfate
South Korea15 participantsStarted 2013-03-20
Plain-language summary
The purpose of this study is to evaluate efficacy and safety of additional hyaluronic acid/chondroitin sulfate to transurethral resection of bladder ulcer in patient with interstitial cystitis.
Who can participate
Age range20 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. must have experienced bladder pain, urinary urgency and urinary frequency, for at least 6 months prior to entry into the study
✓. Pain VAS ≥4
✓. O'Leary-Sant Interstitial Cystitis questionnaire (IC-Q) symptom and problem ≥ 12( and pain ≥2, and nocturia ≥ 2)
✓. PUF score ≥ 13
✓. cystoscopic record within 2 years
✓. Hunner ulcer lesion in cystoscopic finding
Exclusion criteria
✕. Scheduled for or use of intravesical therapy (eg, bladder distention,transurethral resection of bladder ulcer, instillation) during or within 6months prior to the study and use of pentosan polysulfate sodium within 1 months prior to the study
✕. Patients who are pregnancy or, childbearing age without no contraception
✕. Patients with voided volume \<40 or, \> 400ml
✕. Patients with microscopic hematuria, (≥1+ in dipstick), If not excluded that no evidence of neoplastic tumor examination
✕. Patients with urine culture showing evidence of urinary tract infection 1month prior to the study
✕. Accompanied medical problem below
✕. Patients had prior surgery (eq, bladder augmentation, cystectomy
What they're measuring
1
Change of pain scores on the Visual Analogue Scale