Efficacy of Laser Versus Cryotherapy in the Treatment of Warts

Inclusion Criteria: * Patients have cutaneous warts, including common warts(d≥1cm or n≥5 ), plantar warts, periungual warts, mosaic warts, which are suitable for cryotherapy and laser treatment . * patients aged eighting years and over, who have junior school degree or above Exclusion Criteria: * Patients who have more than 20 warts * Patients who are currently participating in another trial for the treatment of their warts * Patients who took immunosuppressant drugs such as oral corticosteroids within the past three months. * Patients who are pregnant or ready for pregnancies or breast-feeding. * Patients who have impaired healing eg due to diabetes, vascular disease, vitamin A deficiency, hyperthyroidism and hypothyroidism. * Patients who have autoimmune diseases, eg SLE, dermatomyositis, scleroderma and other diseases . * Patients who have cold intolerance, eg cold urticaria, cryoglobulinaemia, cold agglutinin syndrome, Raynaud's syndrome. * Patients who have local injections intolerance. * Patients who have local hypoesthesia . * Patients who can not tolerate cryotherapy or laser treatment for their own reasons.