CompletedNot Applicable

Cardiovascular Risk Profile in Patients With Congenital Adrenal Hyperplasia

France170 participantsStarted 2011-05

Plain-language summary

Treatment with glucocorticoids and mineralocorticoids has changed congenital adrenal hyperplasia (CAH) from a fatal to a chronic lifelong disease. Long-term treatment, in particular the chronic (over-)treatment with glucocorticoids, may have an adverse effect on the cardiovascular risk profile in adult CAH patients. The objective of this study was to evaluate the cardiovascular risk profile of adult CAH patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria : patients * Patients \> 18 yrs with classical or non classical CAH diagnosed during childhood * Absence of known cardiovascular disease * Absence of combined oral contraceptives during the previous month Inclusion criteria : controls * Age \> 18 yrs * Absence of known cardiovascular disease * Absence of combined oral contraceptives during the previous month Exclusion criteria : * Blood donation during the previous 3 months * Cardiovascular disease * Treatment by combined oral contraceptives * Pregnancy

What they're measuring

Ultrasound evaluation of intima-media thickness

Timeframe: day 1

Trial details

NCT IDNCT01807364

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-09

View on ClinicalTrials.gov More Congenital Adrenal Hyperplasia trials