CompletedPhase 2

Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine

Brazil11 participantsStarted 2012-03

Plain-language summary

Carbohydrates (CHO)-based drinks 2h before the induction of anesthesia are recommended to decrease insulin resistance. The addition of glutamine (GLN) in these beverages may enhance the benefits of CHO alone. However, only a few studies tested the safety of this formula. The objective of this study was to evaluate the gastric residual volume (GRV) after the intake of a beverage containing CHO plus GLN using magnetic resonance (MRI).

Who can participate

Age range21 Years – 30 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Young male volunteers (aged between 21 and 30 years-old) with body mass index (BMI) between 20 and 29 kg/m2 and without either acute or chronic illness in the last 3 months. Exclusion Criteria: * non-adherence to any phase of the study protocol, * gastroesophageal reflux disease, * previous history of intolerance to lactose, * gastroparesis or history of poor gastric emptying, * diabetes mellitus, and * previous abdominal surgery

What they're measuring

Gastric residual volume (GVR) ("change" is being assessed)

Timeframe: immediately after ingestion (T0), 120 minutes after (T120) and 180 (T180) minutes after ingestion

Trial details

NCT IDNCT01798342

SponsorFederal University of Mato Grosso

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-06

View on ClinicalTrials.gov More Pulmonary Aspiration of Gastric Contents trials