CompletedNot Applicable

Genetics of Latent Autoimmune Diabetes in Adults

United States, United Kingdom205 participantsStarted 2011-07

Plain-language summary

This is a prospective study that will study adults and has the objective of examining 'Latent Autoimmune Diabetes in Adults' (LADA) to understand how this trait is influenced by genetic factors.

Who can participate

Age range25 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed type 2 Diabetes (T2D) patient with: BMI \<30 at diagnosis; Age \>25-\<50 at diagnosis OR * Diagnosed type 1 Diabetes (T1D) patient with: Age \>25 at diagnosis OR \- Currently Diagnosed with LADA with age at initial diagnosis of Diabetes \>25 years and a positive GAD65 antibody test Exclusion Criteria: * Any underlying disease or condition that is a contraindication for obtaining 18.0 ml of blood. * Inability to obtain an informed consent from a given LADA case. * Blood sampling has already occurred for a given subject. * Previous GAD65 antibody test(s) negative.

What they're measuring

Identify variations in the human genome associated with LADA by genotyping cases and comparing allele frequencies to an existing control database

Timeframe: 5 years

Trial details

NCT IDNCT01793974

SponsorChildren's Hospital of Philadelphia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-11

View on ClinicalTrials.gov More Latent Autoimmune Diabetes in Adult trials