CompletedNot Applicable

Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss

United States79 participantsStarted 2013-01

Plain-language summary

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

Who can participate

Age range18 Years – 35 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI ≥ 30.0 kg/m\*m. * Self-reported history of regular menstrual cycles, irregular menstrual cycles, or PCOS. * Absence of hormonal contraception, fertility therapy, or insulin-sensitizing medication in the three months prior to enrollment. Exclusion Criteria: * Pregnant, breastfeeding, or lactating * Lack of one or both ovaries and/or uterus * Previous diagnosis of bleeding disorder(s) or current use of blood thinners/anticoagulants * Vegan or gluten free * Soy or peanut allergy

What they're measuring

Change From Baseline Ovulatory/Menstrual Function

Timeframe: Up to 7 months

Trial details

NCT IDNCT01785719

SponsorCornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-21

Results submitted2024-12-04

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