CompletedNot Applicable

The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver

Austria40 participantsStarted 2013-03

Plain-language summary

The CUSA (cavitron ultrasound surgical aspirator) is the method of choice for hepatic resection in our center. Recently a stapler-hepatectomy methods has been developed and approved for liver surgery using Covidien Endo-Gia stapler. The potential benefit of this method is a potential shorter transection time compared to the CUSA technique. Thus the investigators will perform a randomized controlled trial including 20 patients in the stapler-group and 20 patients in the CUSA control group. Primary endpoint will be transection speed. Secondary endpoints will be peri-operative (d-1, d0, d1, d3) cytokines concentration, T cell subsets, blood loss, morbidity, and a cost analysis.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients scheduled for elective major hepatic resection at the Department of General Surgery, Medical University of Vienna * Stapler hepatectomy and CUSA resection feasible based on preoperative imaging * Age equal or greater than 18 years * Informed consent Exclusion Criteria: * Minor hepatectomy * Hepatitis B, Hepatitis C, HIV infection, autoimmune disease * Inflammatory conditions of the bowel such as Crohn's Disease * Pregnancy

What they're measuring

transection speed

Timeframe: during surgery

Trial details

NCT IDNCT01785212

SponsorMedical University of Vienna

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

View on ClinicalTrials.gov More Liver Neoplasms trials