Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis (NCT01784458) | Clinical Trial Compass
CompletedNot Applicable
Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis
46 participantsStarted 2009-03
Plain-language summary
* Intra-abdominal pressure(IAP) is defined as a steady state pressure of the abdominal cavity
* many studies have proved IAP as a prognostic factor that elevated IAP influences hemodynamics and multiple organs dysfunction
* In previous studies, most of them was based on the septic patients of medical diseases. And it is rare about sepsis of surgical diseases such as traumatized or postoperative patients
* We hypothesized that intra-abdominal hypertension may affect clinical course such as length of stay of intensive care unit, weaning of mechanical ventilation, proceeding of enteral feeding and mortality
* Our study was aimed to investigate prevalence of IAH and risk factors and to analyze clinical course and prognosis influenced by IAH in surgical patients with severe sepsis
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* older than 18-year
* agreed on informed consent
* diagnosed with severe sepsis
Exclusion Criteria:
* traumatic injuries on urethra or bladder
* open abdomen status
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study looked at how high pressure inside the abdomen affects outcomes in surgical patients with severe sepsis — if I have one of these conditions like bowel perforation or peritonitis, how does intra-abdominal pressure factor into how my care team would monitor and manage my treatment?
2Since this trial is completed, has my doctor seen or reviewed any of its findings, and do those results change how they might approach my case compared to standard practice?
3The study enrolled patients with severe sepsis alongside conditions like abscess or bowel leakage — how would my doctor decide whether controlling abdominal pressure is a priority in my specific situation, and what would that monitoring actually look like day to day?
4Because this was an observational study measuring what happens rather than testing a new treatment, are there any interventional trials or established treatment protocols my doctor would recommend based on what research like this has shown?
5If intra-abdominal hypertension turned out to be a significant risk factor in this study, is that something my care team would actively screen for in my case, and what would they do if they found it?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
effects of intra-abdominal hypertension on clinical course and outcome in surgical patients with severe sepsis
Timeframe: within 60 days after admission in surgical intensive care unit